10 exam-style questions with answers and explanations, straight from our 1,030-question bank. Tap an answer to check yourself. When you're ready, take the scored version in the free practice test.
The CCTC exam has 175 questions and runs 3 hours.
These 10 free CCTC questions are organized by exam domain, so you can see how each part of the Certified Clinical Transplant Coordinator blueprint is tested. Reveal the answer and explanation under each question.
A medically cleared living kidney donor tells the coordinator privately, "I do not want to donate, but I do not want my brother told why." Surgery is scheduled for next week. The brother then calls to ask whether the donor has a medical problem. Which response protects the donor's rights?
Correct answer: D - Honor the donor's withdrawal and preserve confidentiality when explaining that donation will not proceed.
At an annual visit, a 42-year-old kidney recipient asks about shingles vaccination. He is 18 months post-transplant, with stable graft function and no rejection in the past year. He takes maintenance tacrolimus, mycophenolate, and prednisone, has documented childhood varicella, and has never received a zoster vaccine. Which recommendation is appropriate?
Correct answer: A - Offer two doses of recombinant zoster vaccine without interrupting the maintenance immunosuppressive regimen.
During transition planning, a 17-year-old liver recipient accurately names his medications and fills a pill organizer. He missed two doses this month because a refill was not ordered. His mother usually orders refills but will be away for several weeks; insurance coverage and pharmacy delivery remain available. What should be the next teaching goal?
Correct answer: A - Demonstrate a refill request and track remaining supply, with caregiver backup.
A kidney transplant candidate has a calculated panel-reactive antibody (cPRA) value of 98%. For an ABO-compatible donor offer, the HLA laboratory reports no donor-specific antibodies and a negative crossmatch using a current serum specimen. The candidate asks, "Does 98% mean this kidney has a 98% chance of being rejected?" Which interpretation should guide discussion of this offer?
Correct answer: A - The cPRA describes donor incompatibility in the population, not rejection probability for this kidney.
A 52-year-old patient begins evaluation for a first kidney transplant on January 12, with a GFR of 24 mL/min. The first documented GFR below 20 is 18 mL/min on March 6. The patient is first registered on the waiting list on June 20, when GFR is 16 mL/min. Maintenance dialysis for end-stage renal disease begins on August 9 of the same year. Which date starts kidney waiting-time accrual under OPTN rules?
Correct answer: C - June 20
A 58-year-old liver transplant candidate received three hemodialysis treatments during the seven days before the current serum creatinine measurement. The measured creatinine is 1.2 mg/dL. When validating the MELD 3.0 inputs, what creatinine value should be used in the score calculation?
Correct answer: C - 3.0 mg/dL
Four months after kidney transplantation, a recipient develops hand tremor and a creatinine increase from 1.1 to 1.9 mg/dL. Potassium is 5.7 mEq/L. Fluconazole was started five days ago; the tacrolimus dose was unchanged. A correctly timed 12-hour tacrolimus trough is 19.6 ng/mL against the patient's target of 6-9 ng/mL. Ultrasound shows patent graft vessels and no hydronephrosis. Which explanation best accounts for the combined findings?
Correct answer: C - Tacrolimus toxicity from a fluconazole interaction
On postoperative day 6 after liver transplantation, a recipient's AST rises from 85 to 3,400 U/L. A technically adequate Doppler study shows no hepatic arterial flow, while portal venous flow remains patent. The recipient is awake and hemodynamically stable. Of the following proposed actions, which has priority?
Correct answer: B - Alert the transplant surgeon for immediate assessment of hepatic arterial occlusion.
A lung recipient's FEV1 has remained at 2.0 L for four months after evaluation and treatment of reversible causes. Infection, acute rejection, and airway obstruction have been excluded, and the team has established chronic lung allograft dysfunction (CLAD). The two best post-transplant FEV1 measurements were 3.1 L and 3.3 L, obtained six weeks apart. Under ISHLT criteria, which CLAD stage should be recorded?
Correct answer: B - Stage 2
Routine surveillance five months after a first kidney transplant detects plasma BK polyomavirus DNA of 18,500 copies/mL. Two weeks later, the same assay measures 27,000 copies/mL. Creatinine remains 1.1 mg/dL, donor-specific antibodies are absent, and the adult recipient has low immunologic risk with no rejection history. Which management plan should the coordinator anticipate from the transplant nephrologist?
Correct answer: C - Reduce maintenance immunosuppression stepwise and follow plasma BK DNA closely.
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